 

#  Gene Editing Shows Promise for Alleviating Hearing Loss 

 





December 20, 2017

 

 

 An early experiment demonstrates the shutting down of a faulty gene by Lydia Denworth

 When David Liu first heard about a strain of mouse from his colleague Zheng-Yi Chen, he got excited. The mice carry a gene, *TMC1*, with a mutation that leads to deafness over time, giving them the name Beethoven mice. Their mutation matches one in humans that produces the same effect. The mutation is dominant; if it is present, hearing loss is certain.

 Liu, a chemical biologist at the Broad Institute, works with the noted CRISPR-Cas9 technology, which targets and changes precise stretches of DNA. [Read More](https://www.scientificamerican.com/article/gene-editing-shows-promise-for-alleviating-hearing-loss/)



 

 

 



 

 

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