Camille Frayssinhes

Camille Frayssinhes

Randy Trumbower, Ph.D.
Spaulding Rehabilitation Hospital’s Department of Physical Medicine and Rehabilitation
Project Title: Modulation of interlimb mechanics during walking in people with incomplete spinal cord injury
Camille Frayssinhes photo

Project summary: The spinal cord is a bundle of nerves that runs from the brain down through the spine and is responsible for carrying messages between the brain and the rest of the body, allowing for movement, sensation, and organ function. When the spinal cord is injured, the messages are interrupted and can result in partial or complete loss of sensory and motor function below the level of the injury. Incomplete spinal cord injuries (iSCI) are important because unlike a complete SCI, they may allow for some remaining function and sensation to be retained. This can lead to a wider range of possible recovery outcomes and potential for rehabilitation. The reacquisition and preservation of walking ability are highly valued goals in iSCI rehabilitation. Indeed, walking is very important for the prevention of and reduction in negative secondary health conditions, greater life expectancy, and improved quality of life after injury. The ability to coordinate the four limbs is an essential feature of human locomotion, allowing to maintain stability in an ever-changing environment. This process requires flexible coordination of the neuromuscular system. However, limited research exists in the understanding of the interlimb coordination for people with iSCI. Moreover, current clinical walking tests are limited in their ability to identify the underlying mechanisms of coordinated walking in people with iSCI. Therefore, my project focuses on developing robust measures that can capture coordination across all the degrees of freedom involved in walking. These measures should be sensitive enough to detect subtle changes in coordination patterns that may be indicative of underlying neuromechanics of walking. This understanding can guide targeted and more effective rehabilitation interventions that aim to improve interlimb mechanics deficits observed in people with iSCI. Ultimately, this can lead to improved walking ability, independence, and quality of life in these people.

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