Project Summary: Organoid models of Alzheimer’s and Parkinson’s disease using induced pluripotent stem cells (iPSCs) derived from diseased patients have been developed recently as model systems to study disease mechanisms. The 3D organoid model system...
Project Summary: This project combines behavioral analysis, mathematical modeling, and simulation, as well as functional imaging in behaving larval zebrafish. We are trying to see how normal fish behaves in society differently from fish with mutated...
Project Summary: In the Andermann lab, I investigate the neural circuits involved in the mating behavior of mammals. Using this behavioral model, I hope to understand how neurons and cells, which are governed by events on the millisecond scale, can...
Project Summary: Current computational models of visual processing focus on the bottom-up cascade of sequential operations from the retina onto primary visual cortex and higher level processing. Here we seek to understand how task goals modulate the...
Project Summary: Electron Microscopy (EM) connectomics aims to build comprehensive maps of connections within an organism's nervous system. Serial EM provides us with detailed anatomical information about neurons and their connections.
Automated methods...
Project Summary: Electrical stimulation is a common tool to interact with neural networks, for both research and clinical purposes. A typical example is deep brain stimulation (DBS) that is used to treat various diseases including Parkinson’s disease or...
Project Summary: To successfully guide behaviour, individual neurons have to integrate multiple sources of information across different modalities. For example, previous studies in perceptual decision making have implicated the integration of multiple...
