News

Call for Proposals: Bertarelli Collaborative Awards for Sensory Disorders

July 13, 2018

Submit by September 1, 2018, 5:00 p.m. EST

The Bertarelli Program in Translational Neuroscience and Neuroengineering is now accepting applications for Bertarelli Collaborative Awards for Sensory Disorders. The program, funded by the Bertarelli Foundation, will bridge the gap between basic and translational neuroscience through research oriented towards translational opportunities and through creation of stronger ties among scientists, engineers and...

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Published article from Bertarelli PI and former Fellow: Dara Manoach and Fikret Işık Karahanoğlu

June 15, 2018

Diffusion-weighted imaging evidence of altered white matter development from late childhood to early adulthood in Autism Spectrum Disorder

Autism Spectrum Disorder (ASD) is thought to reflect disrupted development of brain connectivity characterized by white matter abnormalities and dyscoordination of activity across brain regions that give rise to core features. But there is little consensus about the nature, timing and location of white matter abnormalities as quantified with diffusion-weighted MRI...We examined the...

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Hearing Loss and the Brain

May 3, 2018

Hearing loss is the most common neurological disorder, affecting an estimated 360 million adults and children worldwide, according to the World Health Organization. Yet there are no biological treatments to restore hearing once it’s lost.

Harvard Medical School faculty members are determined to change that.

Take Jeffrey R. Holt, PhD, an HMS professor of otolaryngology and neurology and director of otolaryngology research at the F.M. Kirby Neurobiology Center at Boston Children’s Hospital. He conducts research on “sensory hair cells,” the tiny inner-ear...

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Mass Eye And Ear performs first FDA-approved gene therapy procedure for inherited disease

March 23, 2018
Read article how Mass Eye and Ear performs first FDA-approved gene therapy procedure for inherited disease: http://bit.ly/2pAiyus Dr. Katherine High, President and Chief Scientific Officer, will speak about Luxturna treatment at the Bertarelil Symposium on April 11. To register, visit https://bertarelli.hms.harvard.edu/... Read more about Mass Eye And Ear performs first FDA-approved gene therapy procedure for inherited disease

Gene Editing Shows Promise for Alleviating Hearing Loss

December 20, 2017

An early experiment demonstrates the shutting down of a faulty gene by Lydia Denworth

When David Liu first heard about a strain of mouse from his colleague Zheng-Yi Chen, he got excited. The mice carry a gene, TMC1, with a mutation that leads to deafness over time, giving them the name Beethoven mice. Their mutation matches one in humans that produces the same effect. The mutation is dominant; if it is present, hearing loss is certain.

Liu, a chemical biologist at the Broad Institute, works with the noted CRISPR-Cas9 technology, which targets and...

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