People

Alex Fratzl

Faculty Mentor: Mark Andermann, Ph.D.

Department of Medicine, Beth Israel Deaconess Medical Center

Project Title: Visualizing functional properties of retinal axonal boutons in the dLGN in vivo

Project Summary: Relay neurons in the lateral geniculate nucleus of the thalamus (dLGN) exhibit diverse and sharp visual tuning, suggesting functionally specific convergence of retinal ganglion cell (RGC) axons onto dLGN neurons. However, technical...

Camille Frayssinhes

Randy Trumbower, Ph.D.

Spaulding Rehabilitation Hospital’s Department of Physical Medicine and Rehabilitation

Project Title: Modulation of interlimb mechanics during walking in people with incomplete spinal cord injury

Project summary: The spinal cord is a bundle of nerves that runs from the brain down through the spine and is responsible for carrying messages between the brain and the rest of the body, allowing for movement, sensation, and organ function. When the...

Nicolas Fumeaux

Faculty Mentor: Sydney S. Cash, M.D., Ph.D.

Department of Neurology, Massachusetts General Hospital

Project Title: Deep learning for seizure prediction in a rat model of epilepsy

Project Summary: Nicolas worked on using iEEG recordings in an animal model of epilepsy to predict occurrence of spontaneous seizures. Mesial temporal lobe epilepsy, which is the most common form of focal epilepsy in humans, is obtained in animals with an...

Olivia Gozel

Faculty Mentor: John Maunsell, PhD

Department of Neurobiology, Harvard Medical School

Project Summary: The neuronal mechanisms of attention take place without our awareness. Nevertheless, they play a critical role in determining what we experience. In the visual system, attention filters sensory stimuli by emphasizing important objects or...

Amélie Guex

Faculty Mentor: Daniel J. Lee, M.D., F.A.C.S.

Massachusetts Eye and Ear Infirmary Department of Otology and Laryngology

Project Summary: The focus of this project is to study the use of pulsed laser light to stimulate the central auditory system. This novel approach may be a means to improve the efficacy of the current generation of electrically based Auditory Brainstem...

Niko Guirlinger

Paola Arlotta, Ph.D.

Harvard Department of Stem Cell and Regenerative Biology

Project Title: Elucidating determinants of the developmental speed of corticogenesis

Project Summary: The human brain has always intrigued the global community. Unfortunately, the lack of adequate experimental models has hindered our understanding of human brain development. Indeed, animal models are not suitable to study the human...

Anthony Jakob

Faculty Mentor: Samuel Gershman, Ph.D.

Department of Psychology and Center for Brain Science, Harvard University

Project Title: Neural signatures of policy compression

Curriculum Vitae Project Summary: The brain is subject to computational resource constraints. As such, one can theorize that, in the context of reinforcement learning, it has evolved to balance reward maximization against the cognitive cost of...

Efe Karabeyli

Faculty Mentor: Carl-Fredrik Westin, Ph.D.

Brigham and Women’s Hospital, Department of Radiology

Project Summary: This project focused on the development of a new and robust approach to investigate the compressed sensing technologies for brain imaging. Mr. Karabeyli will work with the lab’s algorithmic development team and learn about current...

Amanda Klaeger

Faculty Mentor: Adam Cohen, Ph.D, Howard Hughes Medical Institute Investigator

Department of Chemistry and Chemical Biology, Harvard University

Project Title: Optical Electrophysiology in Zebrafish

Project Summary: To understand the function of neural circuits in the brain and spinal cord, one would like to perturb specific neurons and to measure the response of the targeted and neighboring cells. Optical methods provide approaches for both...

Kriton Konstantinidis

Faculty Mentor: Emery N. Brown, M.D., Ph.D.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital

Project Title: Fitting adaptive autoregressive models for frequency analysis of non-stationary EEG data via hybrid Kalman filtering

Project Summary: High quality frequency spectra are crucial in anesthesia related procedures that demand real-time high-resolution estimation of the frequency content of the Electroencephalogram (EEG) for efficient brain state tracking. The main target of...

Constantin Krempp

Faculty Mentor: Sydney S. Cash, M.D., Ph.D.

Department of Neurology, Massachusetts General Hospital

Project Title: Single pulse electrical stimulation for epileptic seizures prediction and sleep neuromodulation

Project Summary: Electrical stimulation is a common tool to interact with neural networks, for both research and clinical purposes. A typical example is deep brain stimulation (DBS) that is used to treat various diseases including Parkinson’s disease or...

Vanessa Laversenne

Faculty Mentor: Marcie Glicksman, PhD

Laboratory for Drug Discovery in Neurodegeneration, Harvard NeuroDiscovery Center

Project Title: Bioactive Compound Screen Based on a CD33 Assay for Alzheimer's Disease

Project Summary: The project is a drug discovery project in Alzheimer's disease from assay design to hit confirmation at the LDDN. The aim is to optimize a screen based on CD33 cell surface expression. Indeed it has been discovered that CD33, a protein...